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:: Section 4How does it work?
The Turbuhaler is an example of a multidose reservoir powder system preloaded with a quantity of pure drug sufficient for dispensing 200 doses. The particle size of the drug powder ranges from 1 to 2 µm, but the particle size of the carrier can range from approximately 20 to 65 µm. So, most of the carrier is deposited in the oropharynex. Optimal performance for each DPI design occurs at a specific inspiratory flow rate. The fine particle fraction of respirable drug from existing DPIs ranges from 10% to 60% of the nominal dose. Turbuhaler |
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