:: Section 1
Learning Objectives
After reviewing this module, you should be able to:
- Identify 4 advantages and 4 disadvantages of administering medications via aerosols.
- Define the following terms in relationship to medicinal particles: (a) Stability, (b) Penetration, (c) Deposition.
- Determine by particle size the most likely site of deposition.
- Explain how the following physical properties affect particle deposition: (a) Impaction, (b) Diffusion, (c) Gravity, (d) Temperature, (e) Humidity.
- Discuss how breathing patterns and inspiratory flow rates affect deposition.
- Discuss the advantages and disadvantages of various aerosol generators:(a) Small Volume Nebulizer (SVN), (b) Meter Dose Inhaler (MDI), (c) Dry Powder Inhaler (DPI).
- Discuss the proper technique for delivering medicine using (a) SVN, (b) MDI, (c) DPI.
- Explain the quantity of lung deposition and methods to enhance delivery.
- Explain how to selectively target deposition within the lungs at the upper airways, bronchioles, or alveoli level.
- Discuss how a therapist measures the efficacy of drug administration.
- List examples of drugs you may preferentially administer within the lungs and determine the site of deposition.
- Determine the advantage of using a spacer device when using a MDI.
- Contrast the equivalent dosage required to deliver a beta agonist with a SVN compared to a MDI or a DPI.
- Discuss the impact of different gases (air, oxyegn and heliox gas) used to power the small volume nebulizer.
- Discuss the disadvantages of CFC (chlorofluorocarbons) and HFA (hydrofluoroalkanes) and the lung deposition difference between CFC and HFA.
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