Dr. Hale Z. TOKLU

MS, PhD. Pharmacology

Dept. of Pharmacology & Therapeutics

E-mail: halezerrin@ufl.edu

Office (ARB/ R5-126): +1 352-392-3395

Lab (ARB/R5-183): +1 352-273-9143








2001-2006:  Pharmacology

Institute of Health Sciences, Marmara University, Turkey

Thesis title: The effects of riluzole in early and late phase of sepsis-induced encephalopathy in rats




1998-2001:  Pharmacology

Institute of Health Sciences, Marmara University, Turkey

Thesis title: The effects of glutamate release inhibitor riluzole on morphine dependence and tolerance development



1994-1998:  Pharmacy

College of Pharmacy, Marmara University, Turkey

Graduation project title: Antioxidant vitamins in health and disease



Professional Experience


Research Faculty



University of Florida, Dept. Of Pharmacology & Therapeutics, College of Medicine, Gainesville, FL

Adjunct Professor



Dept. of Sciences for Health Programs (Anatomy & Physiology), Santa Fe College, Gainesville, FL



Geriatric Research Education & Clinical Center, Veterans Affairs Medical Center, Gainesville, FL

Associate Professor


Dept. Of Pharmacology, Marmara University, Istanbul, Turkey

Associate Professor


Dept. Of Pharmacology, Near East University, Nicosia, Cyprus

Assistant Professor


Dept. Of Pharmacology, Marmara University, Istanbul, Turkey

Lecturer/Postdoctoral fellow


Dept. Of Pharmacology, Marmara University, Istanbul, Turkey

Teaching Assistant


Dept. Of Pharmacology, Marmara University, Istanbul, Turkey


Courses/ Teaching



·         Anatomy & Physiology

·         Clinical Pharmacy

·         General Pharmacology

·         Medical Pharmacology

·         OTC Prescribing

·         Pharmacotherapy

·         Pharmacovigilance

·         Rational Drug Use I

·         Rational Drug Use II



·         Introduction to Pharmacotherapy

·         Drug Interactions

·         Herbal Medicine and Food Supplements

·         Rational Drug Use

·         Pharmacovigilance


Books / Chapters



A Proteomic Evaluation of Sympathetic Activity Biomarkers of the Hypothalamus-Pituitary-Adrenal Axis by Western Blotting Technique Following Experimental Traumatic Brain Injury. Methods Molecular Biology, Vol. 1598, Firas H. Kobeissy and Stanley M. Stevens, Jr. (Eds): Neuroproteomics (2017), Springer Nature

Authors: Hale Z. Toklu, Yasemin Sakarya, Nihal Tumer


Blood Brain Barrier Permeability and Brain Edema Due To Traumatic Brain Injury in

Brain Neurotrauma: Molecular, Neuropsychological and Rehabilitation Aspects in Brain Injury Models; Taylor & Francis Group Co. (2015)

Editor Kobeissy F.

Authors: Nihal Tumer, Hale Z. Toklu


Pharmacist Profile in Turkish Republic of Northern Cyprus

Near East University Publications; 2013, Nicosia, Turkish Republic of Northern Cyprus

Authors: Mertdogan Soyalan, Fatma Azgin, Rumeysa Demirdamar, Hale Z. Toklu


Pharmacovigilance Handbook for Pharmacists

Near East University Publications; 2013, Nicosia, Turkish Republic of Northern Cyprus

Authors: Rumeysa Demirdamar, Şahan Saygı, Mertdogan Soyalan, Hale Z. Toklu


Drug Use Profile and Health Expenditure between 2007-2012 in Turkish Republic of Northern Cyprus

Near East University Publications; 2013, Nicosia, Turkish Republic of Northern Cyprus

Authors: Mertdogan Soyalan, Hale Z. Toklu, Şahan Saygi, Rumeysa Demirdamar


Rational Use of Medicine for Pharmacists

Social Security Institution of Turkey; 2013, Ankara, Turkey

Authors: Hale Z. Toklu, Ahmet Akici

Editor: Ahmet Akici



Honors & Awards





Alberto Ferrari Prize, 25th European Meeting on Hypertension and Cardiovascular Protection, Milan, Italy


American Heart Association Trainee Onsite Award, Hypertension Meeting, Washington DC, USA


Scientific research award, Turkish Neurosurgical Society


Pharmaceutical and medicinal chemistry drug design and development third award, Novartis Pharmaceuticals


Scientific research award, Turkish Neurosurgical Society


Best presentation second award, MEFKO (Colleges of Pharmacy National Meeting)



Outstanding academic achievement award Marmara University College of Pharmacy



Best presentation second award, 6th South Eastern European Meeting


Best oral presentation award, Society of Neurosurgery




Award of encouragement and support for international publications, Marmara University



Professional membership




Association for Florida Colleges


International Society for Pharmacoepidemiology


Society for Neuroscience


American Heart Association/ American Stroke Association


American Society of Pharmacology & Experimental Therapeutics (ASPET)


Turkish Association of Brain Research and Neuroscience


Society of Pharmacovigilance


Society of Brain Research


Clinical Pharmacy Association


Turkish Pharmacological Society


Editor/ Editorial/ Advisory Board


Frontiers in Neurotrauma


International Journal of Hospital Pharmacy


Journal of Pharmacovigilance


JSM Health Education and Primary Health care


Clinical Experimental Health Sciences


Journal of Pharmaceutical Care & Health Systems


Webmed Central (Pharmacology Editor)


Bulletin of the Turkish Pharmacological Society


Near East Medical Journal


Marmara Pharmaceutical Journal



Peer reviewed articles


Lab Science / Animal Research


1.     Toklu HZ, Yang Z, Oktay S, Sakarya Y, Kirichenko N, Matheny MK, Muller-Delp J, Strang K, Scarpace PJ, Wang KKW, Tumer N. Overpressure blast injury-induced oxidative stress and neuroinflammation response in rat frontal cortex and cerebellum. Behav Brain Res. 2017 Apr 15. pii: S0166-4328(17)30632-0. doi: 10.1016/j.bbr.2017.04.025

2.     Toklu HZ, Scarpace PJ, Sakarya Y, Kirichenko N, Matheny M, Bruce EB, Carter CS, Morgan D, Tumer N. Intracerebroventricular tempol administration in older rats reduces oxidative stress in the hypothalamus but does not change STAT3 signalling or SIRT1/AMPK pathway. Appl Physiol Nutr Metab. 2017 Jan;42(1):59-67. doi: 10.1139/apnm-2016-0067.

3.     Toklu HZ, Sakarya Y, Matheny M, Kirichenko N, Bruce E, Carter CS, Morgan D, Scarpace PJ , Tumer N. Anorexic response to rapamycin does not appear to involve a central mechanism. Clin Exp Pharmacol Physiol. 2016 Sep;43(9):802-7

4.     Ekiz A, Ozdemir-Kumral ZN, Ersahin M, Tugtepe H, Ogunc AV, Akakin D, Kiran D, Ozsavci D, Biber N, Hakan T, Yegen B, Sener G, Toklu HZ. Functional and structural changes of the urinary bladder following spinal cord injury; treatment with alpha lipoic acid. Neurourol Urodyn. 2017 Apr;36(4):1061-1068

5.     Tinay I, Sener TE, Cevik O, Cadirci S, Toklu H, Cetinel S, Sener G, Tarcan T. Antioxidant Agent Quercetin Prevents Impairment of Bladder Tissue Contractility and Apoptosis in a Rat Model of Ischemia/Reperfusion Injury. Low Urin Tract Symptoms. 2017 May;9(2):117-123. doi: 10.1111/luts.1

6.     Toklu HZ, Toklu HZ, Muller-Delp J, Sakarya Y, Oktay S, Kirichenko N, Matheny M, Carter CS, Morgan D, Strehler K, Tumer N, Scarpace PJ. High dietary fructose does not exacerbate the detrimental consequences of high fat diet on basilar artery function. J Physiol Pharmacol 2016 Apr;67(2):205-16

7.     Strehler KYE, Matheny M, Kirichenko N, Sakarya Y, Bruce E, Toklu HZ, Carter CS, Morgan D, Tumer N, Scarpace PJ. Onset of Leptin Resistance Shows Temporal Differences Related to Dose or Pulsed Treatment. Eur J Pharmacol 2016 May 15;779:177-85

8.     Bruce E, Carter CS, Yasemin S, Matheny MK, Kirichenko N, Toklu HZ, Morgan D, Tumer N, Scarpace PJ. Rapamycin Reduces Bodyweight and Improves Leptin Signaling in a Rodent Model of Diet-Induced Obesity. (revision submitted)

9.     Yarrow JF, Toklu HZ, Balaez A, Phillips EG, Otzel DM, Chen C, Wronski TJ, Aguirre JI, Sakarya Y, Tumer N, Scarpace PJ. Fructose consumption does not worsen bone deficits resulting from high-fat feeding in young Male rats. Bone. 2016 Feb 5. pii: S8756-3282(16)30027-8. doi: 10.1016/j.bone.2016.02.004.

10.   Toklu HZ, Muller-Delp J, Yang Z, Oktay Ş, Sakarya Y, Strang K, Ghosh P, Delp MD, Scarpace PJ, Wang KK, Tumer N. The functional and structural changes in the basilar artery due to overpressure blast injury. J Cereb Blood Flow Metab. 2015 Dec;35(12):1950-6. 

11.   Kwon OS, Smuder AJ, Wiggs MP, Hall SE, Sollanek KK, Morton AB, Talbert EE, Toklu HZ, Tumer N, Powers SK. AT1 receptor blocker losartan protects against mechanical ventilation-induced diaphragmatic dysfunction. J Appl Physiol (1985). 2015 Sep 10:jap.00237.2015.

12.   Carter CS, Khamiss D, Matheny M, Toklu HZ, Kirichenko N, Strehler KY, Tumer N, Scarpace PJ, Morgan D. Rapamycin Versus Intermittent Feeding: Dissociable Effects on Physiological and Behavioral Outcomes When Initiated Early and Late in Life. J Gerontol A Biol Sci Med Sci. 2015 Jan 23. pii: glu238.

13.   Scarpace PJ, Matheny M, Strehler KY, Toklu HZ, Kirichenko N, Carter CS, Morgan D, Tumer N. Rapamycin Normalizes Serum Leptin by Alleviating Obesity and Reducing Leptin Synthesis in Aged Rats. J Gerontol A Biol Sci Med Sci. 2015 Jan 23. pii: glu230.

14.   Tumer N, Toklu HZ, Muller-Delp JM, Oktay S, Ghosh P, Strang K, Delp MD, Scarpace PJ. The effects of aging on the functional and structural properties of the rat basilar artery. Physiol Rep. 2014 Jun 6;2(6). pii: e12031

15.   Toklu HZ, Kwon OS, Sakarya Y, Powers SK, Llinas K, Kirichenko N, Sollanek KJ, Wiggs MP, Smuder AJ, Talbert EE, Scarpace PJ, Tumer N. The effects of enalapril and losartan on mechanical ventilation-induced sympathoadrenal activation and oxidative stress in rats. J Surg Res. 2014 Feb 6. pii: S0022-4804(14)00093-6. 

16.   Kobeissy F, Mondello S, Tumer N, Toklu HZ, Whidden MA, Kirichenko N, Zhang Z, Prima V, Yassin W, Anagli J, Chandra N, Svetlov S, Wang KK. Assessing neuro-systemic & behavioral components in the pathophysiology of blast-related brain injury. Front Neurol. 2013 Nov 21;4:186.

17.   Sılay MS, Toklu H, Özağarı A, Aydın M, Tetik Ş, Şener G, Miroğlu C, Kendirci M. Montelukast prevents testes against ischemia-reperfusion injury through suppression of iNOS expression. Turk J Urol. 2014 Dec;40(4):221-7. doi: 10.5152/tud.2014.61587.

18.   Toklu HZ, Kabasakal L, Imeryuz N, Kan B, Celikel C, Cetinel S, Orun O, Yuksel M, Dulger GA. A study comparing the efficacy of antimicrobial agents versus enzyme (P-gp) inducers in the treatment of 2,4,6 trinitrobenzenesulfonic acid-induced colitis in rats. J Physiol Pharmacol. 2013 Aug;64(4):439-51.

19.   Ersahin M, Ozsavcı D, Sener A, Ozakpinar OB, Toklu HZ, Akakin D, Sener G, Yegen BC. Obestatin alleviates subarachnoid haemorrhage-induced oxidative injury in rats via its anti-apoptotic and antioxidant effects. Brain Inj. 2013;27(10):1181-9

20.   Cevik O, Ersahin M, Sener TE, Tinay I, Tarcan T, Cetinel S, Sener A, Toklu HZ, Sener G. Beneficial effects of quercetin on rat urinary bladder after spinal cord injury. J Surg Res. 2013 Aug;183(2):695-703.

21.   Ersahin M, Toklu HZ, Erzık C, Akakin D, Tetık S, Sener G, Yegen BC. Ghrelin alleviates spinal cord injury in rats via its anti-inflammatory effects. Turk Neurosurg. 2011;21(4):599-605

22.   Ozsavci D, Ersahin M, Sener A, Ozakpinar OB, Toklu HZ, Akakin D, Sener G, Yegen BC. The novel function of nesfatin-1 as an anti-inflammatory and antiapoptotic peptide in subarachnoid hemorrhage-induced oxidative brain damage in rats. Neurosurgery. 2011 Jun;68(6):1699-708

23.   Hakan T, Toklu HZ, Biber N, Celik H, Erzik C, Ogunc AV, Cetinel S, Sener G. Meloxicam exerts neuroprotection on spinal cord trauma in rats. Int J Neurosci. 2011 Mar;121(3):142-8.

24.   Ersahin M, Toklu HZ, Akakin D, Yuksel M, Yegen BC, Sener G. The effects of Nigella sativa against oxidative injury in a rat model of subarachnoid hemorrhage. Acta Neurochir (Wien). 2011; 153(2):333-41.

25.   Toklu HZ, Hakan T, Celik H, Biber N, Erzik C, Ogunc AV, Akakin D, Cikler E, Cetinel S, Ersahin M, Sener G. Neuroprotective effects of alpha-lipoic acid in experimental spinal cord injury in rats. J Spinal Cord Med. 2010;33(4):401-9.

26.   Toklu HZ, Sehirli O, Ersahin M, Suleymanoglu S, Yiginer O, Emekli-Alturfan E, Yarat A, Yegen BC, Sener G. Resveratrol improves cardiovascular function and reduces oxidative organ damage in the renal, cardiovascular and cerebral tissues of two-kidney, one-clip hypertensive rats. J Pharm Pharmacol. 2010; 62(12):1784-93.

27.   Ersahin M, Toklu HZ, Erzik C, Cetinel S, Akakin D, Velioglu-Ogunc A, Tetik S, Ozdemir ZN, Sener G, Yegen BC. The anti-inflammatory and neuroprotective effects of ghrelin in subarachnoid hemorrhage-induced oxidative brain damage in rats. J Neurotrauma. 2010 Jun;27(6):1143-55.

28.   Ersahin M, Toklu HZ, Cetinel S, Yuksel M, Erzik C, Berkman MZ, Yegen BC, Sener G. Alpha Lipoic Acid Alleviates Oxidative Stress and Preserves Blood Brain Permeability in Rats with Subarachnoid Hemorrhage. Neurochem Res. 2010 Mar;35(3):418-28.

29.   Velioglu-Ogunc A, Sehirli O, Toklu HZ, Ozyurt H, Mayadagli A, Eksioglu-Demiralp E, Erzik C, Cetinel S, Yegen BC, Sener G. Resveratrol protects against irradiation-induced hepatic and ileal damage via its anti-oxidative activity. Free Radic Res. 2009 Aug 25:1-12.

30.   Hakan T, Toklu HZ, Biber N, Ozevren H, Solakoglu S, Demirturk P, Aker FV. Effect of COX-2 inhibitor-meloxicam against traumatic brain injury induced biochemical, histopathological changes and blood brain barrier permeability. Neurol Res 2010 Jul;32(6):629-35.

31.   Ersahin M, Sehirli O, Toklu HZ, Suleymanoglu S, Emekli-Alturfan E, Yarat A, Tatlidede E, Yegen BC, Sener G. Melatonin improves cardiovascular function and ameliorates renal, cardiac and cerebral damage in rats with renovascular hypertension. J Pineal Res. 2009; 47(1):97-106

32.   Biber N, Toklu HZ, Solakoglu S, Gultomruk M, Hakan T, Berkman Z, Dulger G. Cysteinyl-leukotriene receptor antagonist montelukast decreases blood-brain barrier permeability but does not prevent edema formation in traumatic brain injury. Brain Injury 2009, 23:577-84.

33.   Toklu HZ, Sehirli O, Ozyurt H, Mayadagli A, Demiralp E, Cetinel S, Sahin H, Yegen B, Ulusoylu Dumlu M, Gokmen V, Sener G. Punica Granatum Peel Extract Protects Against Ionizing Radiation-Induced Enteritis And Leukocyte Apoptosis In Rats. J Radiat Res (Tokyo). 2009;50(4):345-53.

34.   Toklu HZ, Hakan T, Biber N, Solakoglu S, Ogunc AV, Sener G. The protective effect of alpha lipoic acid against traumatic brain injury in rats. Free Rad Res 2009 Jul;43(7):658-67.

35.   Ersahin M, Toklu HZ, Cetinel S, Yuksel M, Yegen BC, Sener G. Melatonin reduces experimental subarachnoid hemorrhage-induced oxidative brain damage and neurological symptoms. J Pineal Res. 2009 Apr;46(3):324-32.

36.   Karakus S, Kocyigit -Kaymakcioglu B, Toklu HZ, Aricioglu F, Rollas S. Synthesis and anticonvulsant activity of new N-(alkyl/sub-stituted aryl)-N'-[4-(5-cyclohexylamino)-1,3,4-thiadiazole-2-yl)phenyl]thioureas. Arch Pharm (Weinheim). 2009 Jan;342(1):48-53.

37.   Toklu HZ, Keyer Uysal M, Kabasakal L, Sirvanci S, Ercan F, Kaya M. The Effects of Riluzole on Neurological, Brain Biochemical, and Histological Changes in Early and Late Term of Sepsis in Rats. J Surg Res. 2009 Apr;152(2):238-48.

38.   Kocyigit-Kaymakcioglu B, Toklu HZ, Ikiz S, Bagcigil AF, Rollas S, Ozgur NY, Ak S. Synthesis and antinociceptive-antimicrobial activities of some new amide derivatives of 3,5-di/-and 1,3,5-trimethylpyrazoles. J Enzyme Inhib Med Chem. 2008 Aug;23(4):454-61.

39.   Toklu HZ, Tunali-Akbay T, Velioglu-Ogunc A, Ercan F, Gedik N, Keyer-Uysal M, Sener G. Silymarin, the antioxidant component of Silybum marianum, prevents sepsis-induced oxidative injury of lung and brain. J Surgical Research 2008 145(2) 214-222

40.   Toklu HZ, Dumlu MU, Sehirli O, Ercan F, Gedik N, Gokmen V, Sener G. Pomegranate peel extract prevents liver fibrosis in biliary-obstructed rats. J Pharm Pharmacol. 2007 Sep;59(9):1287-95.

41.   Sener G; Sehirli O; Toklu H; Ercan F; Alican I. Montelukast Reduces Ischemia/Reperfusion-Induced Bladder Dysfunction and Oxidant Damage in the Rat. J Pharmacy Pharmacol 2007, 59:837-842

42.   Dulundu E, Ozel Y, Topaloglu U, Toklu H, Ercan F, Gedik N, Sener G Grape Seed Extract Reduces Oxidative Stress and Fibrosis in Experimental Biliary Obstruction Journal of Gastroenterology and Hepatology 2007 Jun;22(6):885-92.

43.   Toklu HZ, Tunali T, Erkanlı G, Yuksel M, Ercan F, Sener G. Silymarin, the antioxidant component of Silybum marianum, protects against burn-induced oxidative skin injury. Burns 2007 33 (7): 908-916.

44.   Sener G, Sehirli AO, Toklu HZ, Yuksel M, Ercan F, Gedik N. Erdosteine treatment attenuates oxidative stress and fibrosis in experimental biliary obstruction. Pediatr Surg Int. 2007 Mar;23(3):233-41.

45.   Sener G, Toklu HZ, Cetinel S: b-glucan protects against chronic nicotine-induced oxidative damage in rat kidney and bladder. Environmental Toxicology Pharmacology 23 (1) 2007, 25-32

46.   Toklu HZ, Alican I, Ercan F, Sener G: The beneficial effect of resveratrol on rat bladder contractility and oxidant damage following ischemia/reperfusion. Pharmacology. 2006 Aug 21;78(1):44-50

47.   Toklu HZ., Sehirli AO, Velioglu-Ogunc A., Cetinel S., Sener G. Acetaminophen-induced toxicity is prevented by β-D-glucan treatment in mice. European Journal Pharmacology Volume 543, Issues 1-3, 14 August 2006, Pages 133-140

48.   Sener G., Toklu HZ, Sehirli AO, Velioglu-Ogunc A, Cetinel S, Gedik N. Protective Effects of Resveratrol Against Acetaminophen-Induced Toxicity In Mice. Hepatology Res. 2006; 35(1): 62-68.

49.   Toklu HZ, Sener G, Jahovic N, Uslu B, Arbak S, Yegen BC. Beta-glucan protects against burn-induced oxidative organ damage in rats. Int Immunopharmacol. 2006 Feb;6(2):156-69.

50.   Sener G, Toklu HZ, Erkanli G, Ercan F. Protective Effect of β-Glucan Against Oxidative Organ Injury in a Rat Model of Sepsis. Int Immunopharmacol. 2005 Aug;5(9):1387-96.

51.   Sener G, Toklu H, Kapucu C, Ercan F, Erkanlı G, Kacmaz A, Tilki M, Yegen BC. Melatonin Protects Against Oxidative Organ Injury In A Rat Model Of Sepsis. Surgery Today 2005; 35(1):52-59.

52.   Sener G, Paskaloglu K, Toklu H, Kapucu C, Ayanoglu-Dulger G, Kacmaz A, Sakarcan A. Melatonin ameliorates chronic renal failure-induced oxidative organ damage in rats. Journal of Pineal Research 2004; 36(4): 232-241


Under maiden name


53.   Oruc EE, Kocyigit-Kaymakcioglu B, Oral B, Altunbas-Toklu HZ, Kabasakal L, Rollas S. Synthesis of some novel azo derivatives of 3,5-dimethyl-1-(2-hydroxyethyl) pyrazole as potent analgesic agents. Arch Pharmazie (Weinheim). 2006 May;339(5):267-72.

54.   Aricioglu F, Altunbas H. Harmane induces anxiolysis and antidepressant-like effects in rats. Annals of New York Academy of Science 2003; 1009: 196-201

55.   Aricioglu F, Altunbas H. Agmatine an endogenous anxiolytic/ antidepressant agent? Annals of New York Academy of Science 2003; 1009: 136-140

56.   Sener G, Sehirli AO, Altunbas HZ, Ersoy Y, Paskaloglu K, Arbak S, Ayanoglu-Dulger G. Melatonin protects against gentamicin-induced nephrotoxicity in rats. Journal of Pineal Research 2002; 32(4): 231-236



Human Studies/ Pharmacy Practice/ Education



57.   Toklu HZ. Pharmacovigilance of Herbal Medicine: Herbavigilance. Adv. Pharmacoepidemiol. Drug Saf. 2016; 5(4):208

58.   Toklu HZ, Mensah E. Why do we need pharmacists in pharmacovigilance systems? Online Journal of Public Health Informatics 2016; 8(2):e193

59.   Toklu HZ, Soyalan M, Gultekin O, Ozpolat M, Aydin MD, Gunay AC, Akici A, Ozkum D, Demirdamar R. The knowledge and attitude of the health professionals towards pharmacovigilance and adverse drug reaction reporting in Northern Cyprus. J Pharmacovigilance 2016; 4: 193.

60.   Toklu HZ. Promoting evidence-based practice in pharmacies. Integrated Pharmacy Research and Practice 2015;4 127-131

61.   Toklu HZ. Pharmaceutical Education Vs. Pharmacy Practice: Do We Really Teach What They Need For Practicing? J Pharma Care Health Sys 2015, S3:e001. doi:10.4172/2376-0419.S3-e001

62.   Toklu HZ. Rational use of medicine in pharmacy practice. Turkiye Klinikleri J Pharmacol (special topics) 2015; 3(1):74-83

63.   Toklu HZ, Hussain A. The changing face of pharmacy practice and the need for a new model of pharmacy education. J Young Pharm. 2013 Jun;5(2):38-40.

64.   Toklu HZ. Problem based pharmacotherapy teaching for pharmacy students and pharmacists. Curr Drug Deliv. 2013 Feb;10(1):67-70.

65.   Toklu HZ, Demirdamar R. The evaluation of prescription dispensing scores of the pharmacy students before and after the problem-based rational drug use course: Results of the two years experience. Marmara Pharm J. 2013; 17(3): 175-180.

66.   Ozkum D, Akı O, Toklu HZ. Herbal medicine use among diabetes mellitus patients in Northern Cyprus. J Med Plant Res. 2013;7(22):1652-64.

67.   Toklu HZ, Dulger GA, Hıdıroğlu S, Akici A, Yetim A, Gannemoğlu HM, Gunes H. Knowledge and attitudes of the pharmacists, prescribers and patients towards generic drug use in Istanbul - Turkey. Pharm Pract (Granada). 2012 Oct;10(4):199-206.

68.   Gokcekus L, Toklu HZ, Demirdamar R, Gumusel B. Dispensing practice in the community pharmacies in the Turkish Republic of Northern Cyprus. Int J Clin Pharm. 2012 Apr;34(2):312-24.

69.   Toklu HZ, Demirdamar R, Gumusel B, Yaris E, Dulger G. Rational drug use awareness of the nurses in the Turkish Republic of Northern Cyprus Near East University Hospital. Marmara Pharm J 2012; 16(2): 150-154

70.   Demirdamar R, Toklu HZ, Gumusel B. Pharmacy education in Turkish Republic of Northern Cyprus. Educational Research 2012; 3(1):1-6.

71.   Toklu HZ, Akıcı A, Keyer Uysal M, Dülger G. The role of the doctor and pharmacist in improving patient compliance in the process of rational drug use. Turkısh J Family Practice. 2010; 14(3): 139-145

72.   Toklu HZ, Akici A, Oktay S, Cali S, Sezen SF, Keyer-Uysal M. Pharmacy practice of community pharmacists in Turkey. Marmara Pharm J, 2010; 14(1):53-60.

73.   Toklu HZ, Keyer-Uysal M. The knowledge and attitude of the Turkish community pharmacists toward pharmacovigilance in the Kadikoy district of Istanbul. Pharmacy World Science 2008 Oct;30(5):556-62.

74.   Akıcı A, Kalaca S, Ugurlu U, Toklu HZ, Oktay S. Antihypertensive drug utilization at health centers in a district of Istanbul. Pharmacy World & Science 2007 Jun;29(3):116-21.

75.   Akıcı A, Kalaca S, Ugurlu MU, Toklu HZ, Iskender E, Oktay S. Patient knowledge about drugs prescribed at primary healthcare facilities. Pharmacoepidemiology and Drug Safety 2004 Dec; 13(12): 871-876.