Interests: Toxicology, Pharmacology, Physiology, Insect Control ;
Education:

University of California, Riverside.
Degree: Ph.D., Entomology, December, 1986
Specialization: Insect Physiology (Department Major), Insecticide Toxicology (Department Minor), Biochemistry (Outside Minor)
Major Professor: Thomas A. Miller.
Dissertation: A pharmacological Study of the Hyperneural Muscle of Periplaneta americana L.
Coursework: Insect Neurophysiology, Insect Biochemistry, Insecticide Toxicology, General Pharmacology.

University of California, Riverside.
Degree: M.S., Entomology, August, 1981.
Specialization: Economic Entomology.
Major Professor: Robert A. VanSteenwyk.
Thesis: Feasibility of Marking the Cabbage Looper, Trichoplusia ni (Hubner), and the Pink Bollworm, Pectinophora gossypiella (Saunders), with Cesium.
Coursework: Insecticide Toxicology, Statistics, General Biochemistry, Economic Entomology, Biological Control, Insect Ecology.

San Diego State University
Degree: B.S., Zoology, June, 1977
Coursework: Cell Physiology, Botany, Vertebrate Anatomy, Ecology, Genetics, Zoology, Insect Biological Control, Acarology, Economic Entomology, Insect Physiology, General Entomology.

Santa Rosa Junior College.
Degree: A.S., June, 1975
Coursework: Organic Chemistry, Physics.

Palomar College.
Degree: None (1974) GPA: 3.55
Coursework: Chemistry, Biology, Trigonometry, general ed.

1969 - 1973: U. S. Coast Guard (Independent Duty Medic).

Experience:

June 1 2018 to present: Retired.

Dec 2006 to May 30, 2018: Chemist, technician/Lab manager. University of Florida, Department of Animal Sciences. Research on environmental factors that affect vertebrate embryos. Research on stressors that disrupt embryonic function and development, and the cellular systems that limit these effects. Stressors include heat, chemicals, lack or excess of oxygen, and combinations of factors. Factors that improve cryoperservation for improved direct embryo transfer pregnancy rates in cattle.

May 2004 to September 2006: Research technician/Lab manager. Pharmacogenomics research support. Discover genetic polymorphisms affect the response to drugs. This includes various methods for analysis of the composition (sequence) human genetic material (DNA or RNA) and storage and retrieval of that information for analysis with clinical records of drug responses. Pharmacogenomics is the study of how an individual's genetic inheritance affects the body's response to drugs.

September 2002 to April 2004: Postdoctoral researcher, University of Florida. Adipocyte (fat cell) pharmacology research.

July 2001 to June 2002: Histologist (Electron Microscopy) at VA Medical Center, Gainesville, Florida. They fired me because I forgot to wear my lab coat when I went upstairs.

January 1998 to July 2001: Research technician. Used molecular techniques in research in cellular regulation of gene expression involved in mammalian development and cancer. DNA cloning, PCR, blots, protein manipulations and related techniques.

June 1994 to January 1998: Substitute teaching in public schools. Completed development of an insecticidal boric acid synergist (patent 5,667,816) which was developed and marketed. A label for the boric acid composition was approved by the Environmental Protection Agency (EPA). Consulted on the health effects of drugs, pesticides, insect repellents and other chemical exposures. Wrote a review for the U.S. Senate Committee on Veterans Affairs which dealt with the potentiation of the toxicity of a drug used by Persian Gulf War troops, by pesticides and other substances. Member of a research team that studied the effects of chemical risk factors related to Persian Gulf War illnesses.

July 1990 to June 1994: Research Entomologist, USDA ARS, Medical and Veterinary Entomology Research Laboratory, Gainesville, Florida.

General responsibilities were investigating insecticide resistance, synergism, and modes of action. Developed a method for monitoring for insecticide resistance in German cockroaches. Found that some pyrethroid insecticides may have toxic actions which may be unrelated to the known action on the sodium channel. Also found that there may be an unexpected action by some carbamate insecticides which may be from non cholinesterase effects. Collaborated in studies to improve uses of boric acid based baits for ants and fleas. Also collaborated in tests of repellents for fleas. Conducted studies on the mode of action of boric acid which led to the discovery of several boric acid co synergists. Found some new synergists for formamidine pesticides.

Conducted mode of action studies on an insect repellent (DEET) which suggested a possibility for the toxic action of DEET. Began an investigation of chemical and physical insect control methods which could serve as alternates to the fumigant methyl bromide, which depletes ozone and has been scheduled to be discontinued.

March 1989 to June 1990: Research Entomologist, USDA ARS Subtropical Horticulture Research Laboratory, Miami, Florida.

The primary goal of the laboratory was the reduction of quarantine insect pests.

Evaluated the kinetics of thermal death in the Caribbean fruit fly, to improve methods of estimating heat treatment times needed for required killing rates. Initiated a project in which fruit fly disinfestation of fruit by heat was augmented by wrapping the fruit so that internal oxygen levels would be reduced, which reduced the temperature and time needed to kill the insects. Cooperated on a project in which adenosine triphosphate (ATP) depletion was used as a measure of heat induced mortality to Fuller rose beetle eggs.

February 1987 to February 1989: Research Associate (two year post doctoral appointment) USDA ARS Tropical Fruit and Vegetable Research Laboratory, Hilo, Hawaii.

Part of my research was an investigation of lethal effects of heat on different embryo (egg) stages of the Mediterranean fruit fly. Found that heat susceptibility varies with the developmental stage of the embryo, and oxygen availability.

August 1981 to December 1986: Research Assistant (Ph.D. program), University of California, Riverside.
Investigated the effects of extracts from insect tissue on contractile responses of the hyperneural muscle (an insect Avisceral muscle) of the American cockroach (Periplaneta americana). Also studied the effects of neurochemicals on the muscle to characterize the pharmacological properties of the muscle.

June 1976 to July 1981: Research Assistant (M.S. program), University of California, Riverside.
Tested the ability of saturated pheromone environments to prevent mating in pink bollworms (Pectinophora gossypiella). Tested the feasibility of using cesium as a marker (for dispersal studies) for pink bollworms and cabbage loopers. The insects were successfully marked by feeding on cesium treated diet,greenhouse cotton plants, and field grown cotton plants.

Professional Activities:
American Association For the Advancement of Science 18 yr.
American Chemical Society, 6 yr.
Entomological Society of America 19 yr.
Florida Entomological Society 5 yr.
American Society of Zoologists 3 yr.

Publications:

Estrada E, Ortiz WG,Chebel RC,Jannaman EA, Moss JI, Cavallari de Castro F,Zolini AM,Staples CR, Hansen PJ. Embryo and cow factors affecting pregnancy per embryo transfer for multiple-service, lactating Holstein recipients. Transl. Anim. Sci. 2019. doi: 10.1093/tas/txz009

Tribulo P, Jumatayeva G, Lehloenya K, Moss JI, Negron-Perez VM, Hansen PJ. Effects of sex on response of the bovine preimplantation embryo to insulin-like growth factor 1, activin A, and WNT7A. BMC Dev Biol. 2018 Jul 28;18(1):16. doi: 10.1186/s12861-018-0176-2. PMID: 30055575

Tribulo P, Moss JI, Ozawa M, Jiang Z, Tian XC, Hansen PJ. WNT regulation of embryonic development likely involves pathways independent of nuclear CTNNB1. Reproduction. 2017 Apr;153(4):405-419. doi: 10.1530/REP-16-0610. Epub 2017 Jan 9. PMID: 28069902

Geary TW, Burns GW, Moraes JG, Moss JI, Denicol AC, Dobbs KB, Ortega MS, Hansen PJ, Wehrman ME, Neibergs H, O'Neil E, Behura S, Spencer TE. Identification of Beef Heifers with Superior Uterine Capacity for Pregnancy. Biol Reprod. 2016 Aug;95(2):47. doi:10.1095/ biolreprod.116.141390. Epub 2016 Jul 14.

Tribulo P, Moss JI, Hansen PJ. 190 expression of genes associated with wingless-related mouse mammary tumour virus signaling in the pre-implantation bovine embryo. Reprod Fertil Dev. 2014 Dec;27(1):186. doi: 10.1071/RDv27n1Ab190. PubMed PMID: 25472239.

Lewis MW, Brant JO, Kramer JM, Moss JI, Yang TP, Hansen P, Williams RS, Resnick JL. Angelman syndrome imprinting center encodes a transcriptional promoter. Proc Natl Acad Sci U S A. 2014 Nov 5. pii: 201411261. [Epub ahead of print] PubMed PMID: 25378697.

Dikmen S, Khan FA, Huson HJ, Sonstegard TS, Moss JI, Dahl GE, Hansen PJ. The SLICK hair locus derived from Senepol cattle confers thermotolerance to intensively managed lactating Holstein cows. J Dairy Sci. 2014 Sep;97(9):5508-20. doi: 10.3168/jds.2014-8087. Epub 2014 Jul 2. PubMed PMID: 24996281.

Dobbs KB, Khan FA, Sakatani M, Moss JI, Ozawa M, Ealy AD, Hansen PJ. Regulation of pluripotency of inner cell mass and growth and differentiation of trophectoderm of the bovine embryo by colony stimulating factor 2. Biol Reprod. 2013 Dec 19;89(6):141. doi: 10.1095/biolreprod.113.113183. Print 2013 Dec. PubMed PMID: 24198123.

Moss JI. Gulf War illnesses are autoimmune illnesses caused by increased activity of the p38/MAPK pathway in CD4+ immune system cells, which was caused by nerve agent prophylaxis and adrenergic load. Med Hypotheses. 2013 Dec;81(6):1002-3. doi: 10.1016/j.mehy.2013.09.014. Epub 2013 Sep 17. PubMed PMID: 24095261.

Moss JI, Garrett TJ, Hansen PJ. Involvement of free cholesterol and high-density lipoprotein in development and resistance of the preimplantation bovine embryo to heat shock. J Anim Sci. 2012 Nov;90(11):3762-9. doi: 10.2527/jas.2011-4717. Epub 2012 Jun 4. PubMed PMID: 22665658.

Moss JI. Gulf War illnesses are autoimmune illnesses caused by reactive oxygen species which were caused by nerve agent prophylaxis. Med Hypotheses. 2012 Aug;79(2):283-4. doi: 10.1016/j.mehy.2012.04.043. Epub 2012 May 24. PubMed PMID: 22632735.

Moss JI. Chemical interactions and Gulf War illnesses. Chem Biol Interact. 2011 Aug 15;193(1):107; author reply 108. doi: 10.1016/j.cbi.2011.03.006. Epub 2011 Apr 5. PubMed PMID: 21473857.

Niu Y, Gong Y, Langaee TY, Davis HM, Elewa H, Beitelshees AL, Moss JI, Cooper-Dehoff RM, Pepine CJ, Johnson JA. Genetic variation in the beta2 subunit of the voltage-gated calcium channel and pharmacogenetic association with adverse cardiovascular outcomes in the INternational VErapamil SR-Trandolapril Study GENEtic Substudy (INVEST-GENES). Circ Cardiovasc Genet. 2010 Dec;3 (6):548-55. doi: 10.1161/CIRCGENETICS.110.957654. PubMed PMID: 21156931; PubMed Central PMCID: PMC3060561.

Moss JI, Pontes E, Hansen PJ. Insulin-like growth factor-1 protects preimplantation embryos from anti-developmental actions of menadione. Arch Toxicol. 2009 Nov;83(11):1001-7. doi: 10.1007/s00204-009-0458-3. Epub 2009 Jul 11. PubMed PMID: 19593550.

Moss JI Hansen PJ. Insulin-like growth factor-1 reduces the anti-development effects of menadione on development of bovine preimplantation embryos. American Dairy Science Association, American Society Of Animal Science, July 2008, TH182.

Moss JI. The synergism of N,N-diethyl-m-toluamide (DEET) effects by a carbamate is a novel and new observation. Am J Trop Med Hyg. 2006 Apr;74(4):520; author reply 520. PubMed PMID: 16606976.

Niu YX, Langaee TY, Gong Y, Moss JI, Cooper-Dehoff RM, Pepine CJ, Johnson JA. DNA Variations In Voltage-gated Calcium Channel Beta 2 Subunit (CACNB2) Gene, Functional Consequences, and Association with Adverse Cardiovascular Outcomes In the Iternational Verapamil SR-trandolapril Study-Genetic Substudy. Circulation 118 (18) S885 Suppl. 2 2008 Meeting Abstract

Beitelshees AL, Gong Y, DeHoff RM; Moss JI, Pepine CJ, Johnson JA. Variable blood pressure response to verapamil KCNMB1 genotype. Clinical Pharmacology & Therapeutics, 77 (2): P97 Suppl. S 2005 Meeting Abstract.

Moss JI. Many Gulf War illnesses may be autoimmune disorders caused by the chemical and biological stressors pyridostigmine bromide, and adrenaline. Medical Hypotheses. 2001; 56 (2):155 157. (doi:10.1054/mehy.2000.1129) ISSN: 0306 9877 PMID: 11425278.

Moss, J.I. 1998 (September). Possible Potentiation of Pyridostigmine Bromide (PB) by Pesticides (p. 181-193). In: Report of the Special Investigation Unit on Gulf War Illnesses, Committee on Veteran's' Affairs, United States Senate. S. Prt. 105-39.

Moss, J.I. 1997. U.S. Patent # 5,667,816, September 16 1997. Pest Controlling Composition. (Boric acid insecticide synergists).

Chaney, L.A., Mozingo, J.R., Hume, A.S. & J.I. Moss. 1997. Potentiation of Pyridostigmine Bromide Toxicity in Mice by Selected Adrenergic Agents and Caffeine. Vet. Human Toxicol. 39 (9): 214 219.

Chaney, L., Moss, J., Mozingo, J., & A. Hume. 1997. Toxic interactions between pyridostigmine (PB), N,N Diethyl m toluamide (DEET), adrenergic agents and caffeine. Toxicologist 36(1), P2, p21, #106.

Moss, J.I. 1996. Synergism of Toxicity of N,N Diethyl m toluamide to German Cockroaches (Othoptera: Blattellidae) by Hydrolytic Enzyme Inhibitors. J. Econ. Entomol. 89(5): 1151 1155.

Moss, J.I. & J.G. Scott. 1996. Tetrodotoxin protects German cockroaches from Type I pyrethroid and carbamate insecticide poisoning. J. Econ. Entomol. 89: 51 55.

U.S. Senate (in). 1995. Is Military Research Hazardous to Veterans' Health? Lessons from World War II, The Persian Gulf, and Today. Transcript of Hearing before the Committee on Veterans' Affairs, May 6 1994. S. Hrg. 103 984.

Zhao, R., Klotz, J.H., Moss, J. I. Davis, L. R. & R.S. Patterson. 1995. Laboratory Evaluation of Compounds for Repellency against the Cat Flea, 1994. Arthropod Management Tests. 20: 358 359.

Klotz, J.H. & J.I. Moss. 1996. Oral toxicity of a boric acid sucrose water bait to florida carpenter ants (Hymenoptera: Formicidae). J. Entomological Sci. 31: 9 12.

Zhao, R., Klotz, J.H., Moss, J. I. Davis, L. R. & R.S. Patterson. 1995. Screening Some New Repellents against Cteno cephalides felis. J. Traditional Chinese Veterinary Medicine. 2:36.

Klotz, J.H. & J.I. Moss. 1994. Renewed Interest in an "Ancient" Compound. Pest Control Technology. 22: 55, 58.

Klotz, J.H., Moss, J.I., Zhao, R., Davis, L.R. and R.S. Patterson. 1994. Oral Toxicity of Boric Acid and Other Boron Compounds to Immature Cat Fleas (Siphonaptera: Pulicidae). J. Econ. Entomol. 87: 1534 1536.

Moss, J. I. & H. T. Chan. 1993. Thermal death kinetics of Caribbean fruit fly (Diptera: Tephritidae) embryos. J. Econ. Entomol. 86: 1162 1166.

Moss, J.I., R.S. Patterson and P.G. Koehler. 1992. Detection of insecticide resistance in the German cockroach (Dictyoptera: Blattellidae) with glue toxin traps. J. Econ. Entomol. 85: 1601 1605.

Moss, J.I., R.S. Patterson and P.G. Koehler. 1991. A new technique for the rapid prediction of insecticide resistance in German Cockroaches. Pest Control Technology. 19: 42 46, 102.

Moss, J.I., and E.B. Jang. 1991. Effects of age and metabolic stress on heat tolerance of Mediterranean Fruit Fly (Diptera: Tephritidae) eggs. Journal of Economic Entomology. 84: 537-541.

Sharp, J.L., Gaffney, J.J., Moss, J.I., and W.P. Gould. 1991. Hot Air Treatment Device for Quarantine Research. Journal of Economic Entomology. 84: 520-527.

Forney, C.F., L.H. Aung, D.G. Brandl, E.L. Soderstrom, J.I. Moss. 1991. Reduction of Adenosine Triphosphate in eggs of Fuller rose beetle (Coleoptera: Curculionidae) induced by lethal temperature and methyl bromide. Journal of Economic Entomology. 84: 198 201.

Moss, J.I., and T.A. Miller. 1988. A Pharmacological Study of the Hyperneural Muscle of Periplaneta americana. Journal of Insect Physiology 34: 997 1003.

Moss, J.I., and R.A. VanSteenwyk. 1984. Marking Cabbage Looper (Lepidoptera: Noctuidae) with Cesium. Environmental Entomology. 13(2): 390-393.

Moss, J.I., and R.A. VanSteenwyk. 1982. Marking Pink Bollworm (Lepidoptera: Gelechiidae) with Cesium. Environmental Entomology. 11(6): 1264 1268.

Presentations:

ICAR 17th International Congress on Animal Reproduction (ICAR 2012), Vanvouver BC, July 2012. Involvement of free cholesterol and high density lipoprotein in development and resistance of the preimplantation bovine embryo to heat shock. Moss JI, Garrett TJ, Hansen PJ.

American Dairy Science Association, American Society Of Animal Science, July 2008, TH182 Insulin-like growth factor-1 reduces the anti-development effects of menadione on development of bovine preimplantation embryos. J. I. Moss* and P. J. Hansen, University of Florida, Gainesville.

Society of Toxicology Meeting, March 1997, Cincinnati, OH. Toxic interactions between pyridostigmine (pb), n,n diethyl m-toluamide (DEET), adrenergic agents and caffeine. L. Chaney, J Moss, J. Mozingo and A. Hume.

Entomological Society of America annual meeting, December 1994 Dallas, TX. Oral toxicity of boric acid to ants, fleas, and cockroaches. J. Klotz & J. Moss.

Entomological Society of America annual meeting, December 1993 Indianapolis IN. Tetrodotoxin protects German Cockroaches from Type I Pyrethroid and Carbamate Insecticide Poisoning. J. I. Moss and R. S. Patterson

Presented talk titled "Histological Effects on German Cockroach Midguts Poisoned with Boric Acid" at the annual meeting of the Florida Entomological Society at Captiva Island Naples, Florida on August 9 to 12, 1993.

Presented talk titled "Field trial of German cockroach insecticide resistance monitoring" at the Urban Entomology Research Symposium, at the annual meeting of the Florida Entomological Society at Stuart, Florida on August 10 to 13, 1992.

Annual Meeting, Entomological Society of America (December, 1992): "Field tests of resistance monitoring sticky traps for the German cockroach". J.I. Moss, R. S. Patterson, & P. G. Koehler.

Annual Meeting, Entomological Society of America (December, 1991): "Insecticide resistance monitoring for the German cockroach". J.I. Moss, R. S. Patterson, & P. G. Koehler.

Presented talk titled "Methods for Monitoring Insecticide Resistance in the German Cockroach" at the Urban Entomology Workshop and Symposium, at the annual meeting of the Florida Entomological Society at Naples, Florida on August 4 to 7, 1991.

Presented talk titled "Trap method for monitoring insecticide resistance in the German cockroach" at a workshop on insecticide Resistance in the German cockroach held at Parti University, West Lafayette, Indiana on March 18 19, 1991.
Cornell 15 18 Jan 1991 Insecticide resistance workshop.

Annual Meeting, Entomological Society of America (December, 1989): "The Use of Physiological Studies in the Development of Commodity Treatments." J.I. Moss, E.B. Jang, and J.L. Sharp.

Pacific Branch, Entomological Society of America (June 1988):"Susceptibility of embryo stages of the Mediterranean fruit fly (Ceratitis capitata) to heat treatments" J.I. Moss and E.B. Jang.

International Congress of Entomology (July 1988): "Pharmacological effects on heat induced death of cultured cells of the Mediterranean fruit fly (Ceratitis capitata) (Diptera: Tephritidae)." J.I. Moss and E.B. Jang.
Hawaiian Entomological Society (May 1988): "Studies of the mechanism of thermally induced death in the med fly, Ceratitis capitata." J.I. Moss
Invitations/Consultation:

June 2002. Presented talk on Gulf War Illnesses and related research to the Department of Veterans' Affairs Research Advisory Committee on Gulf War illnesses.

In February, 2002 Presented a seminar on my research on chemical interactions to the Department of Pharmacology, University of Toledo (Toledo, Ohio).

In the Summer of 1997, I contracted to and wrote a report for the U.S. Senate Veterans' Affairs Committee Special Investigation Unit on Persian Gulf War Illnesses. The subject was the interactions of the nerve gas protection pre-treatment, pyridostigmine bromide, with pesticides.

Provided expert testimony to the U.S. Senate Committee on Veterans' Affairs (May 6th 1994) on the subject of possible pesticides interactions; and subsequently served as a consultant to the Committee's Special Investigation Unit on Persian Gulf War Veterans' illnesses in the area of pesticide research.

Invited by the Naval Environmental Health Center to present talk "Detection of Insecticide Resistance in the German Cockroach with Glue Toxin Traps" at the Navy Operational Entomology Training Workshop at the Navy Disease Vector Ecology and Control Center, Naval Air Station, Jacksonville, Florida on February 7, 1992.

Invited to present talk "Methods for Monitoring Insecticide Resistance in the German Cockroach at the Urban Entomology Workshop and Symposium, at the annual meeting of the Florida Entomological Society at Naples, Florida on August 4 to 7, 1991.

Invited to present a paper on "Factors which influence heat induced death in Tephritid embryos and cultured cells" at the USDA ARS, Insects Affecting Man and animals Research Laboratory Gainesville, Florida, January 15th., 1990