Mutant Mouse Information Sheet
Please provide as much information as you have available on your mutant mouse that will undergo pathologic phenotyping.  If there are references for the mutant, please provide either copies of the papers or citation listings.  Please submit this form at or before the time of submission of tissues or animals to the lab.  Thank you.

Transgenic: 
Gene:       Promoter:      
Is expression inducible?     Which inducible/repression system:      
Do you have expression data?       Is expression cell type specific?       
What cell type?      Are antibodies to protein available?      
Are probes for in situ hybidization available?        
Is the gene part of a characterized pathway?        
What type or specific pathway?      
Is homozygosity lethal?       Is there a dose effect?       
What is the expected effect of the transgene?  (Neoplasia, neurologic disorder, degeneration, inflammation, etc)      
Reference citations:      

Knockout: 
Gene:      
What is the normal function of the gene thought to be?      
Is the mutation a null mutation?       Does the mutation delete specific domains?      
Is this a dominant negative mutation?      Is there a knockin (lac-z, luceriferace, GFP)?      
Where is the gene normally  expressed?      Is there a heterozygous phenotype?      
Is the KO cell specific (floxed?)?       Which cells?      
Has the phenotype been rescued?      
What is the expected effect of the knockout?  (Neoplasia, neurologic disorder, degeneration, inflammation, etc)      
Reference citations:      

Insertion Mutants: 
Has the gene been cloned?       What is the gene?       Do you have expression data?       Is expression cell type specific?        What cell type?      Are antibodies to protein available?        
Are probes for in situ hybridization available?        Is the gene part of a characterized pathway?        Is homozygosity lethal?       
Is the gene over-expressed, under-expressed (or null), miss-expressed (spatial or temporal)?       Is the mutation dominant or resessive?      
What is the clinical effect of the insertion?  (Neoplasia, neurologic disorder, degeneration, inflammation, etc) 
Reference citations: