Michael Andrew Bewernitz, Ph.D.
Post Doctoral Associate
Department of Pharmaceutics
The
Education and Experience
●
August 2008 -
present
Post-doctoral associate, Department of
Pharmaceutics, University of Florida
Mentor:
Distinguished
Professor Hartmut Derendorf, Ph.D.
●
May 2008
Ph.D. in biomedical engineering from
the J. Crayton Pruitt Family Department of
Biomedical Engineering,
University of Florida, thesis title: “Data
Mining and Time Series Analysis of Brain Dynamical Behavior with Applications
in Epilepsy”
Mentor:
Distinguished Professor
Panos Pardalos, Ph.D.
●
August 2007
M.E.
in biomedical engineering from the J. Crayton
Pruitt Family Department of Biomedical Engineering,
University of Florida
●
May 2002
B.S. in chemical engineering from the
Department of Chemical Engineering, Michigan State University
*Biochemical engineering specialization* (chemical
engineering specialization option)
Research Interests
●
Pharmacokinetic /
pharmacodynamic modeling with neural recording data
●
Optimizing drug
delivery and dosing for clinical efficacy
●
Discovery of
biomarkers for drug activity
●
Pharamcological
and neurostimulation therapeutic control strategies for neurological disorders
Conference Talks
Basim Uthman, Chang-Chia Liu, Michael Bewernitz, Petros Xanthopoulos. Unverricht-Lundborg
Disease: Challenges in treatment and outcome measures. Conference on
Computational Neuroscience 2008. Feb 21st, 2008.
Michael
Bewernitz, Onur Seref, Basim Uthman,
Panos Pardalos. A Novel Generalized Spike-Wave Detector: Towards Real-Time
Applications in Epilepsy. Conference on
Computational Neuroscience 2008. Feb 21st, 2008.
Nikita Boyko, Michael
Bewernitz, Vitaliy Yatsenko, Panos Pardalos, Basim Uthman, Georges
Ghacibeh. Data Mining Application for Processing EEG Obtained from Epileptic
Patients Treated with Vagus Nerve Stimulation. Conference on
Computational Neuroscience 2008. Feb 21st, 2008.
Michael
Bewernitz, George Ghacibeh, Onur
Seref, Basim Uthman, Panos Pardalos. Support Vector Machine Classification
of EEG Data From Epileptic Patients Treated with Vagus Nerve Stimulation. Data Mining, Systems
Analysis and Optimization in Biomedicine. March 28th, 2007.
Michael
Bewernitz, Jabriel Riley, Zhao Liu,
Paul Carney, Lewis Baxter, J. Chris Sackellares. A Novel In-Vivo Seizure
Model of Frontal Basal Forebrain Origin in an Anolis Lizard. DIMACS
Workshop on Data Mining, Systems Analysis, and Optimization in Neuroscience.
February 15th, 2006.
Publications
Bewernitz M.A., Ghacibeh G., Seref O., Pardalos P.M., Liu C.C.,
Uthman B. Quantification of the Impact of Vagus Nerve Stimulation Parameters
on Electroencephalographic Measures. Proceedings of the conference on Data
Mining, Systems Analysis and Optimization in Biomedicine.
Busygin S., Boyko N., Pardalos P.M., Bewernitz M.A., Ghacibeh G. Biclustering
EEG Data from Epileptic Patients Treated with Vagus Nerve Stimulation.
Proceedings of the conference on Data Mining, Systems Analysis and Optimization
in Biomedicine.
Uthman B., Bewernitz
M.A., Liu C.C., Ghacibeh G. Optimization of Epilepsy Treatment with
Vagus Nerve Stimulation. Proceedings of the conference on Data Mining,
Systems Analysis and Optimization in Biomedicine.
Nair
SP, Bewernitz M. A., Jukkola P.
Seref O., Kundakcioglu O.E., Bewernitz M.A. “Support Vector Machines in Neuroscience”,
in: N. Wickramasinghe and E. Geisler (editors), Encyclopedia of Healthcare
Information Systems,
Carney P.R., Shiau D.S., Iasemidis L.D.,
Suharitdamrong W., Shenk D., Bewernitz
M.A., Nair S.P., Pardalos P.M., Sackellares J.C. Nonlinear Quantitative
EEG Analysis Distinguishes Normal from Seizure-Prone Newborns. AES 58th
Annual Meeting 2004, Dec. 3 - 7,
Patents
Basim
Uthman, Panos Pardalos, Michael Bewernitz, Chang-Chia Liu, Stanislav Busygin.
Variational Parameter Neurostimulation Paradigm for Treatment of Neurologic
Disease.
Marketing
communication from the University of Florida Office of Technology and
Licensing:
http://apps.rgp.ufl.edu/otl/pdf/marketing/12501.pdf
News
article regarding the patent, published in Medical Device & Diagnostic
Industry, © 2008:
http://www.devicelink.com/mddi/archive/08/04/011.html
Research Protocols
Sub-Investigator
An
Exploratory Study to Evaluate the Penetration of JNJ-32729463, A New Fluoroquinolone,
into Soft Tissues Determined by In Vivo Microdialysis in Healthy Subjects. (GCRC #765, IRB #559-2008)
Sub-Investigator
Quantitative
Electroencephalographic and Evoked Potential Changes Resulting from
Brivaracetam Treatment are Associated with Reduction of Myoclonus in Patients
with Unverricht Lundborg Disease. (IRB
#489-2007)
Sub-Investigator
Examining
the Effect of Lamotrigine for Newly Diagnosed Absence Seizures using
Quantitative EEG Analysis. (IRB
# 559-2007)
Sub-Investigator
Differentiating
Status Epilepticus from other Encephalopathies using Quantitative EEG Analysis.
(IRB # 252-2007)
Conference Organization Committee
Conference on Computational
Neuroscience 2008. February 20-21, 2008.
Data Mining, System Analysis
and Optimization in Biomedicine. March 28-30, 2007.
Ad Hoc Reviewer
BIOMAT
2007: International Symposium on Mathematical and Computational Biology. Armação dos Búzios,
Rio de Janeiro, RJ, 24th – 29th November. www.biomat.org
Journal
of Combinatorial Optimization
Awards and Honors
●
Physics
instructor, Science: Optimizing Academic Returns
(SOAR) Project, Science Content
Enrichment Series (High School), funding provided by the Panhandle Area Education Consortium
(PAEC),
●
Teaching
assistantship, Howard-Hughes Medical Institute (HHMI) Science For Life program,
●
Award, Impact Award for community service, presented
by The Dean of Students Office and the Center for Leadership & Service at
the University of Florida, March 27, 2007
●
Honorable
mention, selected to represent
Michigan State University in the American Institute of Chemical Engineering
(AICHE) National Student Design Competition, Spring, 2002
Contact Information
●
Email:
●
Phone:
(352) 273-7855
●
Department of
Pharmaceutics
P3-26, JHMHC
1600
SW Archer Road
University of Florida
●
Mailing
address
Department of
Pharmaceutics
P3-20, JHMHC
1600 SW Archer Road
P.O. Box 100494
Gainesville, FL, 32610
USA
Last updated 6-11-09